Splenectomy for Hematologic Disease

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Vascular complications after splenectomy for hematologic disorders.

The most widely recognized long-term risk of splenectomy is overwhelming bacterial infection. More recently, thrombosis has become appreciated as another potential complication of the procedure. Because of these long-term risks, the indications for and timing of splenectomy are debated in the medical community. Accordingly, the adverse effects and benefits of splenectomy for hematologic disorde...

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Bacterial Infections Following Splenectomy for Malignant and Nonmalignant Hematologic Diseases

Splenectomy, while often necessary in otherwise healthy patients after major trauma, finds its primary indication for patients with underlying malignant or nonmalignant hematologic diseases. Indications of splenectomy for hematologic diseases have been reducing in the last few years, due to improved diagnostic and therapeutic tools. In high-income countries, there is a clear decrease over calen...

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Hematologic outcomes after total splenectomy and partial splenectomy for congenital hemolytic anemia.

PURPOSE The purpose of this study was to define the hematologic response to total splenectomy (TS) or partial splenectomy (PS) in children with hereditary spherocytosis (HS) or sickle cell disease (SCD). METHODS The Splenectomy in Congenital Hemolytic Anemia (SICHA) consortium registry collected hematologic outcomes of children with CHA undergoing TS or PS to 1 year after surgery. Using rando...

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Laparoscopic Splenectomy in Pediatric Patients with Hematologic Diseases

OBJECTIVE The aim of this study was to evaluate our experience with laparoscopic splenectomy in pediatric patients with hematologic diseases. METHODS A retrospective chart review was performed to analyze the following: indication for splenectomy, pre- and peri-operative management, surgical technique, complications, duration of hospitalization, and outcome. RESULTS Eleven patients underwent...

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Laparoscopic versus open splenectomy in the management of hematologic diseases.

UNLABELLED Splenectomy is the best available treatment for severe forms of hereditary spherocytosis, idiopathic thrombocytopenic purpura, and other hematologic conditions when these prove refractory to conservative management. It has been employed for many decades with low mortality and favorable remission rates. The use of laparoscopic splenectomy in recent years has been rapidly and even enth...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1984

ISSN: 0003-4932

DOI: 10.1097/00000658-198407000-00006